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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSP90B1
All Species:
39.09
Human Site:
Y200
Identified Species:
61.43
UniProt:
P14625
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P14625
NP_003290.1
803
92469
Y200
G
Q
F
G
V
G
F
Y
S
A
F
L
V
A
D
Chimpanzee
Pan troglodytes
XP_509323
803
92478
Y200
G
Q
F
G
V
G
F
Y
S
A
F
L
V
A
D
Rhesus Macaque
Macaca mulatta
XP_001095189
804
92594
Y200
G
Q
F
G
V
G
F
Y
S
A
F
L
V
A
D
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P08113
802
92457
Y200
G
Q
F
G
V
G
F
Y
S
A
F
L
V
A
D
Rat
Rattus norvegicus
Q66HD0
804
92752
Y200
G
Q
F
G
V
G
F
Y
S
A
F
L
V
A
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507634
816
93562
Y218
G
Q
F
G
V
G
F
Y
S
A
F
L
V
A
D
Chicken
Gallus gallus
P08110
795
91537
Y199
G
Q
F
G
V
G
F
Y
S
A
F
L
V
A
D
Frog
Xenopus laevis
NP_001083114
805
92996
Y200
G
Q
F
G
V
G
F
Y
S
A
F
L
V
A
D
Zebra Danio
Brachydanio rerio
Q90474
725
83300
G174
F
T
V
K
P
D
F
G
E
S
I
G
R
G
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P02828
717
81847
P167
V
R
A
D
N
S
E
P
L
G
R
G
T
K
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q18688
702
80265
S152
D
D
S
Y
Q
W
E
S
S
A
G
G
S
F
V
Sea Urchin
Strong. purpuratus
NP_999808
806
92314
Y199
G
Q
F
G
V
G
F
Y
S
S
F
L
V
A
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q08277
715
81872
G165
Y
V
W
E
S
Q
A
G
G
S
F
T
V
T
H
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9STX5
823
94185
S201
Q
F
G
V
G
F
Y
S
A
Y
L
V
A
D
Y
Baker's Yeast
Sacchar. cerevisiae
P15108
705
80881
S155
W
E
S
N
A
G
G
S
F
T
V
T
L
D
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.6
N.A.
N.A.
96.6
95.1
N.A.
90.5
90.5
85
44.2
N.A.
44.2
N.A.
43.2
65.2
Protein Similarity:
100
99.8
99.7
N.A.
N.A.
98.5
97.8
N.A.
95.4
95.1
94.1
62.5
N.A.
61.3
N.A.
61.5
81.3
P-Site Identity:
100
100
100
N.A.
N.A.
100
100
N.A.
100
100
100
6.6
N.A.
0
N.A.
13.3
86.6
P-Site Similarity:
100
100
100
N.A.
N.A.
100
100
N.A.
100
100
100
13.3
N.A.
6.6
N.A.
13.3
100
Percent
Protein Identity:
N.A.
46.8
N.A.
47.7
44.4
N.A.
Protein Similarity:
N.A.
63.1
N.A.
67.8
61.2
N.A.
P-Site Identity:
N.A.
13.3
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
20
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
7
0
7
0
7
60
0
0
7
60
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
7
0
7
0
7
0
0
0
0
0
0
0
14
54
% D
% Glu:
0
7
0
7
0
0
14
0
7
0
0
0
0
0
14
% E
% Phe:
7
7
60
0
0
7
67
0
7
0
67
0
0
7
0
% F
% Gly:
60
0
7
60
7
67
7
14
7
7
7
20
0
7
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
7
% I
% Lys:
0
0
0
7
0
0
0
0
0
0
0
0
0
7
0
% K
% Leu:
0
0
0
0
0
0
0
0
7
0
7
60
7
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
7
7
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
7
0
0
7
0
0
0
0
0
0
0
% P
% Gln:
7
60
0
0
7
7
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
7
0
0
0
0
0
0
0
0
7
0
7
0
0
% R
% Ser:
0
0
14
0
7
7
0
20
67
20
0
0
7
0
0
% S
% Thr:
0
7
0
0
0
0
0
0
0
7
0
14
7
7
7
% T
% Val:
7
7
7
7
60
0
0
0
0
0
7
7
67
0
7
% V
% Trp:
7
0
7
0
0
7
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
7
0
0
7
60
0
7
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _